Description
What is Tranexamic Acid?
Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin,Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid.
Function and Application
1.Menstrual bleeding of Pure Tranexamic Acid
2.Orthopedic Surgery of Pure Tranexamic Acid
3.Trauma of Pure Tranexamic Acid
4.Dentistry of Pure Tranexamic Acid
5.In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with
6.In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
7.Whitening effect.Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%
| Product name | Tranexamic Acid | |
| Items | Standards | Results |
| Appearance | White crystalline powder | Complies |
| Solubility | Freely soluble in water and in glacial acetic acid,practically insoluble in alcohol | Complies |
| Identification | Infrared absorption spectrophotometry(2.2.24);IR spectrum is in concordance with tranexamic acid CRS | Complies |
| pH | 7.0~8.0 | 7.2 |
| Related substances liquid chromatography(2.2.29) | ImpurityA≤0.1% | <0.1% |
| ImpurityB≤0.2% | <0.2% | |
| Any other impurity≤0.1% | <0.1% | |
| All other impurity≤0.2% | <0.2% | |
| Heavy metals | ≤10ppm | <10ppm |
| Chlorides | ≤140ppm | <140ppm |
| Loss on dry | ≤0.5% | 0.38% |
| Sulphated ash | ≤0.1% | <0.1% |
| Assay | 99.0%~101.0% | 99.80% |
| Conclusion | Conforms the standard | |
