Description
INTRODUCTION
Cytidylate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine; hence, a ribonucleoside monophosphate. As a substituent it takes the form of the prefix cytidylyl.
USAGE
1. Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
Cytidylate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine; hence, a ribonucleoside monophosphate. As a substituent it takes the form of the prefix cytidylyl.
USAGE
1. Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
2. This product is used as raw material intermediates for the production of nucleotide drugs and food additives, such as raw materials for the synthesis of CTP PolyIC ara-c DDC cdp-choline, and mixed with other nucleotides for health care products and food additives (such as baby milk powder).
| PRODUCT NAME: 5'-Cytidnc Monophosphate Disodium Salt （CMPNa2) | |||
| MOLECULE FORMULA MOLECULE WEIGHT |
C9H12N3O8PNa2 367.2 |
NET WEIGHT TESTING BASED ON |
250kg Costumer requirement |
| Description: White or almost white crystalline powder | |||
| Physicochemical Norms | |||
| Testing Item | Unit | Standard | Result |
| Assay (calc, on dry basis) | % | 98.0-102.0 | 100.92 |
| A 250/260 | / | 0.40-0.52 | 0.45 |
| A 280/260 | / | 1.85~2.20 | 1.98 |
| Loss on Dry | % | Max.26.0 | 19.8 |
| pH (5% solution) | / | 8.0-9.5 | 8.58 |
| Transmittance (5% solution) | % | Min.95 | 99.0 |
| Other nucleotides | % | Max 0.5 | <0.5 |
| Heavy Metals (as Pb) | mg/Kg | Max 10 | <10 |
| Arsenic | mg/Kg | Max 1.5 | <1.5 |
| 1 Lead | mg/Kg | Max 2.0 | <2.0 |
| Bacteriological Norms | |||
| Testing Item | Unit | Standard | Result |
| Total aerobic microbiol count | cfu/ g | Max. 1000 | 20 |
| Coliform | cfu/ g | Max. 10 | <10 |
| Yeast& Moulds | cfu/g | Nmt25 | <10 |
| E.sakazakii | /100g | Absent | Absent |
| Salmonella | /25g | Absent | Absent |
| CONCLUSION: OK/PASS | |||
| Storage/Stability: Stable at room temperature when stored in tightly closed container, protected from humidity. | |||
