Simvastatin CAS 79902-63-9

Description

 INTRODUCTION
What is simvastatin?
Simvastatin is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated cholesterol, or hypercholesterolemia.
It is a member of the statin class of pharmaceuticals. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus.
 
FUNCTION
Function and Application of simvastatin
-Simvastatin is used for lowering blood cholesterol and antihyperlipidemi.
-Simvastatin (INN) is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals.
-The primary uses of simvastatin are for the treatment of dyslipidemia and the prevention of cardiovascular disease.

-Simvastatin also can be used for the patient with coronary heart disease.

Item	Specification	Testing result
Appearance	White or almost white crystalline powder	White crystalline powder
CAS#	147098-20-2	Conforms
Identify	Infrared absorption spectrum should be consistent with the standard spectrum	Associated with the standard spectrum
Water	NMT 3.0%	2.00%
Specific rotation	+16 - +20°	+18.5°
Calcium	3.5% - 4.5%	3.80%
Heavy metal	≤20ppm	Conforms
Single impurity	NMT 0.5%	0.40%
Total impurities	NMT 1.0%	0.80%
Purity	≥99.0%	99.20%
Conclusion	Conformed with EP standard

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